Tap Talk

Developing a mobile phone test to detect risk of Alzheimer’s disease

Tap Talk

Alzheimer’s disease causes about 70% of all dementia and it begins in the brain about 10-20 years before any memory symptoms begin. To reduce dementia incidence, we need to find new ways of detecting Alzheimer’s disease in these early stages. With 200 patients who have mild cognitive impairment or dementia, and 3,000 ISLAND Project research participants, we are developing a new smartphone test called TapTalk that detects early Alzheimer’s disease through hand movement and speech analysis. There is evidence that Alzheimer’s disease causes a slowing of both hand and mouth movements and these changes can be detected if we use computer technologies. We can measure these changes by asking people to tap their fingers and thumbs together, and by analysing how fast people can speak certain syllables such as “pa” and “ta”.  

The Tap Talk project ultimately aims to develop a mobile phone test that can be used by people in the community as well as doctors and nurses in the hospital and clinics to help screen for Alzheimer’s disease across all of its stages – from the pre-clinical stage (without any cognitive symptoms) through to mild cognitive impairment and dementia. If we could detect the leading cause of dementia earlier, we could offer people intense risk modification that can slow or even prevent the onset of dementia in many cases, and/or invite people to new drug trials. The new mobile phone test will be compared to current pen and paper cognitive (memory and thinking) tests, and to blood biomarkers when testing its accuracy. We will also ask participants for their feedback so we make sure it is easy to use.

The Tap Talk project is led by neurologist (medical doctor), Associate Professor Jane Alty, Computer Scientist Associate Professor Quan Bai and speech pathologist, Associate Professor Lyn Goldberg. The project brings together researchers from the Wicking Dementia Centre and College of Science and Engineering as well as clinicians from the Royal Hobart Hospital. It has been funded through a 3 year Major Project grant of approximately $450, 000 from the Royal Hobart Hospital Research Foundation.

You can read our published papers by clicking this link to go to 'Our Publications' and filtering articles for Tap Talk. 

Two people with smartphone